Treat Canine Osteoarthritis (OA) Pain with Galliprant® (grapiprant tablets)

Galliprant is a first-in-class non-COX inhibiting NSAID1 that treats canine OA pain and inflammation early on,** and can be used as long as needed.

Mode of Action

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Galliprant is a non-COX inhibiting NSAID that specifically targets the EP4 receptor, the primary mediator of canine OA pain and inflammation.1

See How Galliprant Works

Targeted Pain Relief

Galliprant works differently to help protect the moments that matter to your patients and their families.


First-in-Class Non-COX Inhibiting NSAID

Galliprant is a prostaglandin receptor antagonist (PRA), a non-COX inhibiting NSAID that specifically blocks the EP4 receptor, the primary mediator of canine OA pain and inflammation.1

Targeted Mode of Action

Galliprant's mode of action targets canine OA pain and inflammation while reducing the impact on GI, kidney and liver homeostasis.1,2†


Use for All Stages of OA

Galliprant can be used for all stages of canine OA, from earliest clinical signs, and can be used as long as needed.*†

Safe to Use Daily

Galliprant is safe to use daily to deliver effective canine OA pain management early on.*

*Approved for use in dogs older than 9 months of age and greater than 8 lbs.
If Galliprant is used long-term, appropriate monitoring is recommended.

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Our concern every time we start any medication is what the risk of safety vs. efficacy is. Anti-inflammatories are the #1 medication we use, and my personal preference is Galliprant.

Dr. Medina, DVM, CVA, CVCH, DACVSMR Rehabilitation Specialist

Dosing and Administration

Most dogs can be dosed once a day with a whole or half tablet:*

  • Prescribe dosage suitable to the dog’s weight
  • Chewable, flavored tablet
  • Appropriate monitoring recommended when used long-term

*Dogs weighing less than 8 lbs cannot be accurately dosed.

Learn How to Dose Galliprant
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You Might Be Interested In…

Understanding how Galliprant works is important, but it doesn’t stop there. Find more useful resources below to get up to speed on canine OA and effective pain management.

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Interactive COAST Tool

COAST is an innovative canine OA staging tool designed by a consortium of international experts in veterinary surgery and pain management. With COAST, you can start the conversation about canine OA with pet owners before it sets in, and monitor OA over time.

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Dosing & Administration

Learn how to prescribe Galliprant to your patients according to their weight.

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Making Galliprant Part of Your Multi-Modal Approach to Managing OA

Start prescribing Galliprant to your OA patients today to provide effective, targeted pain relief for canine OA.


Galliprant is an NSAID that controls pain and inflammation associated with osteoarthritis in dogs.

Important Safety Information

Not for use in humans. For use in dogs only. Keep this and all medications out of reach of children and pets. Store out of reach of dogs and other pets in a secured location in order to prevent accidental ingestion or overdose. Do not use in dogs that have a hypersensitivity to grapiprant. If Galliprant is used long term, appropriate monitoring is recommended. Concomitant use of Galliprant with other anti-inflammatory drugs, such as COX-inhibiting NSAIDs or corticosteroids, should be avoided. Concurrent use with other anti-inflammatory drugs or protein-bound drugs has not been studied. The safe use of Galliprant has not been evaluated in dogs younger than 9 months of age and less than 8 lbs (3.6 kg), dogs used for breeding, pregnant or lactating dogs, or dogs with cardiac disease. The most common adverse reactions were vomiting, diarrhea, decreased appetite, and lethargy. Click here for full prescribing information.

Contact your Elanco or distributor representative, or call Elanco (1-888-545-5973) to discover how you can incorporate Galliprant into your canine OA protocol today.

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